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More than meets the eye: Collision tumors of adenocarcinoma and inflammatory fibroid polyp

  • Xu Wang
    Affiliations
    Department of Gastroenterology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China
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  • Yi Ding
    Affiliations
    Department of Pathology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China
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  • Wei-Feng Huang
    Correspondence
    Corresponding author at: Department of Gastroenterology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
    Affiliations
    Department of Gastroenterology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China

    The School of Clinical Medicine, Fujian Medical University, Fuzhou, China
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Published:February 14, 2023DOI:https://doi.org/10.1016/j.amjms.2023.02.006
      A 47-year-old man presented with a 1-year history of intermittent abdominal pain and hematochezia for 1-week. He had a medical history of diabetes mellitus for 6 years. The physical examination was unremarkable. Laboratory tests showed moderate anemia and positive stool occult blood. Contrast-enhanced computed tomography showed circumferential wall thickening with uneven enhancement in the ascending colon, accompanied by bulky swollen lymph nodes (Fig. 1A). Colonoscopy revealed a large cauliflower-shaped mass occupying the whole lumen in the ascending colon, with necrosis and erosions on the surface (Fig. 1B). Multiple endoscopic mucosal biopsies showed moderately differentiated adenocarcinoma. Following 2 cycles of XELOX (capecitabine/oxaliplatin) chemotherapy, the patient underwent right hemicolectomy and end-to-side anastomosis. Unexpectedly, gross specimen revealed that the upper part of the cut surface was grayish-white and hard in texture with ulcers (Fig. 2A, red circle), while the deeper part was a white nodular lesion, with a homogenously tender texture (Fig. 2A, black circle).
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