Abstract
Rhabdomyolysis is a well-documented side effect of daptomycin and is associated with
hyperuricemia. However, the occurrence of acute gouty arthritis secondary to rhabdomyolysis-induced
hyperuricemia has not been reported. We report a case of a patient who presented with
daptomycin-induced rhabdomyolysis prior to the usual 7-10-day administration period.
This case was complicated with acute gouty arthritis after 7 days from the onset of
rhabdomyolysis symptoms. Treatment consisted of fluid management with the addition
of prednisone for gouty arthritis treatment given his poor kidney function. This report
indicates the importance of early monitoring of creatine kinase levels in patients
on daptomycin to prevent complications from rhabdomyolysis.
Key Indexing Terms
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Article info
Publication history
Published online: January 21, 2023
Accepted:
January 16,
2023
Received:
October 22,
2022
Identification
Copyright
© 2023 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.
