Abstract
Hypertension can cause significant morbidity and reduced life expectancy. Most patients
with hypertension have primary hypertension; however, 10 to 15% of patients have secondary
hypertension. Endocrine disorders explain approximately 10% of hypertension in all
patients, and thyroid disorders account for approximately 1% of cases with hypertension.
Hyperthyroidism can cause increased cardiac output, increased systolic blood pressures,
and increased levels of renin, angiotensin, and aldosterone. Treatment of hyperthyroidism
can cure hypertension in some patients. Consequently, identification of patients with
secondary hypertension potentially has important benefits, and understanding secondary
hypertension provides a framework for investigating the pathophysiology of hypertension.
Clinicians should consider the possibility of hyperthyroidism in patients with hypertension,
even in those of more advanced age.
Keywords
Abbreviations:
WHO (World Health Organization), NHANES (National Health and Nutrition Examination Survey), TR (Thyroid hormone receptor)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: August 10, 2020
Accepted:
August 8,
2020
Received:
April 3,
2020
Footnotes
Financial support: none
Conflicts of interest: The authors have no conflicts of interest to disclose.
Identification
Copyright
© 2020 Published by Elsevier Inc. on behalf of Southern Society for Clinical Investigation.
