Abstract
Background
We sought to establish the characteristics of symptomatic nontyphoidal Salmonella (NTS) urinary tract infection (UTI) without concomitant gastroenteritis (GE) as a
separate clinical entity.
Materials and Methods
We conducted a retrospective cohort single-center study and reviewed all cases of
NTS bacteriuria between 1995 and 2016. Patients were assigned to a group according
to their clinical presentation, namely, symptomatic NTS UTI without GE, GE with NTS
bacteriuria or isolated asymptomatic NTS bacteriuria. We compared the characteristics
of patients in the NTS UTI group to those of the latter 2 groups.
Results
NTS bacteriuria was found in 77 patients, of which 61 had records available for review.
Twenty-one patients (including 17 adults) presented with NTS UTI, 30 patients presented
with features of GE with NTS bacteriuria and 10 patients had asymptomatic NTS bacteriuria.
NTS UTI was not significantly associated with older age, male sex, diabetes, immunosuppressive
states or urologic abnormalities. There was a significant difference in the proportion
of patients with an underlying urologic malignancy in the NTS UTI group (4 of 17 patients
[23.5%]) as compared to those in the other groups (0 of 24 patients), P = 0.023.
Conclusions
A unique group of patients with symptomatic NTS UTI without GE was identified. A significant
association with urologic malignancies was demonstrated in patients with NTS UTI compared
to those with GE and NTS bacteriuria or asymptomatic NTS bacteriuria.
Key Indexing Terms
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Article info
Publication history
Published online: March 23, 2017
Accepted:
March 3,
2017
Received in revised form:
March 2,
2017
Received:
December 16,
2016
Footnotes
☆The authors have no financial or other conflicts of interest to disclose.
Identification
Copyright
© 2017 Southern Society for Clinical Investigation. Published by All rights reserved.
